INT339393

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.06
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tlr4, Nfkb1) signal transduction (Tlr4, Nfkb1) mitochondrion (Nfkb1)
intracellular (Tlr4) DNA binding (Nfkb1) protein complex (Nfkb1)
Tlr4 (Rattus norvegicus)
Nfkb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory response 14 99.12 Very High Very High Very High
Inflammation 38 97.64 Very High Very High Very High
cytokine 42 90.12 High High
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 52 99.12 Very High Very High Very High
Obesity 80 98.52 Very High Very High Very High
Stress 6 93.52 High High
Cancer 4 88.88 High High
Appetite Loss 2 88.32 High High
Necrosis 2 87.84 High High
Endotoxemia 2 71.76 Quite High
Syndrome 10 5.00 Very Low Very Low Very Low
Shock 6 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TLR-4 may activate NF-kB and increase the pro-inflammatory response.
TLR-4 Positive_regulation (activate) of NF-kB associated with inflammatory response
1) Confidence 0.24 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2959201 Disease Relevance 0.52 Pain Relevance 0.14
Toll like receptor 4 may activate NF-kB, which is a transcription factor and increase the pro-inflammatory response.
Toll like receptor 4 Positive_regulation (activate) of NF-kB associated with inflammatory response
2) Confidence 0.24 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2959201 Disease Relevance 1.54 Pain Relevance 0.47

General Comments

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