INT339500

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.31
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Socs1, Eif2ak2) RNA binding (Eif2ak2) intracellular (Eif2ak2)
translation (Eif2ak2) kinase activity (Eif2ak2)
Socs1 (Mus musculus)
Eif2ak2 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 84 89.32 High High
Inflammation 16 5.00 Very Low Very Low Very Low
cytokine 10 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 2 97.48 Very High Very High Very High
Targeted Disruption 6 56.96 Quite High
Sepsis 20 5.00 Very Low Very Low Very Low
INFLAMMATION 18 5.00 Very Low Very Low Very Low
Infection 10 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Bacterial Infection 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Why a loss of SOCS-1 results in dramatically and constitutively elevated levels of phosphorylated PKR, but not total PKR, is not entirely clear.
Negative_regulation (loss) of SOCS-1 Positive_regulation (results) of PKR
1) Confidence 0.05 Published 2010 Journal mBio Section Body Doc Link PMC2962435 Disease Relevance 0.15 Pain Relevance 0.04
Why a loss of SOCS-1 results in dramatically and constitutively elevated levels of phosphorylated PKR, but not total PKR, is not entirely clear.
Negative_regulation (loss) of SOCS-1 Positive_regulation (results) of PKR
2) Confidence 0.05 Published 2010 Journal mBio Section Body Doc Link PMC2962435 Disease Relevance 0.15 Pain Relevance 0.04

General Comments

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