INT33951

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Context Info
Confidence 0.51
First Reported 1986
Last Reported 2010
Negated 4
Speculated 0
Reported most in Body
Documents 18
Total Number 18
Disease Relevance 6.97
Pain Relevance 4.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (TXNRD1) small molecule metabolic process (TXNRD1) cytoplasm (TXNRD1)
cytosol (TXNRD1) signal transduction (TXNRD1) oxidoreductase activity (TXNRD1)
Anatomy Link Frequency
TrA 5
muscle 4
thyroid 1
skin 1
TXNRD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 62 100.00 Very High Very High Very High
monoamine 3 100.00 Very High Very High Very High
Glutamate 8 99.36 Very High Very High Very High
imagery 9 98.48 Very High Very High Very High
c fibre 29 96.40 Very High Very High Very High
backache 20 95.12 Very High Very High Very High
Chronic low back pain 1 93.24 High High
qutenza 33 65.76 Quite High
nMDA receptor 1 55.88 Quite High
Analgesic 3 54.48 Quite High
Disease Link Frequency Relevance Heat
Pain 57 100.00 Very High Very High Very High
Tricuspid Valve Insufficiency 17 100.00 Very High Very High Very High
Nociception 8 99.64 Very High Very High Very High
Toxicity 4 99.54 Very High Very High Very High
Right Ventricular Dysfunction 30 97.32 Very High Very High Very High
Sprains And Strains 8 97.20 Very High Very High Very High
Frailty 1 96.56 Very High Very High Very High
Trigeminal Neuralgia 4 96.04 Very High Very High Very High
Low Back Pain 21 95.12 Very High Very High Very High
Death 4 94.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSION: Percutaneous, controlled RF-TR represents a minimally invasive, low-risk technique with a high rate of efficacy.
Regulation (controlled) of RF-TR
1) Confidence 0.51 Published 2001 Journal Neurosurgery Section Body Doc Link 11270542 Disease Relevance 0 Pain Relevance 0
METHODS: From 1999 to 2001, 18 patients with ITN were treated with percutaneous controlled RF-TR.
Regulation (controlled) of RF-TR
2) Confidence 0.33 Published 2005 Journal Chin. Med. Sci. J. Section Body Doc Link 16261895 Disease Relevance 0.10 Pain Relevance 0
Changes in TrA muscle thickness were greater than the IO muscle during the ADIM for both groups (P<.001).
Regulation (Changes) of TrA in TrA
3) Confidence 0.27 Published 2009 Journal J Orthop Sports Phys Ther Section Body Doc Link 19881003 Disease Relevance 0 Pain Relevance 0
There was no significant difference between groups for changes in TrA muscle thickness (P = 0.055).
Regulation (changes) of TrA in muscle
4) Confidence 0.27 Published 2009 Journal Eur Spine J Section Abstract Doc Link 19015895 Disease Relevance 0.59 Pain Relevance 0.74
It was found that neither the nociceptive motor responses (Tr and Tmr) nor the subjective reports of pain (Tp and Tip), were significantly affected by GB 52.
Neg (neither) Regulation (affected) of Tr associated with nociception and pain
5) Confidence 0.21 Published 1986 Journal Neuropharmacology Section Abstract Doc Link 3022176 Disease Relevance 1.10 Pain Relevance 0.74
BACKGROUND: Although the ADIM has been found to produce a symmetrical change in TrA and IO muscle thickness in healthy subjects, how these muscles are activated in those with unilateral lumbopelvic pain during the ADIM remains unknown.
Regulation (change) of TrA in muscles
6) Confidence 0.16 Published 2009 Journal J Orthop Sports Phys Ther Section Body Doc Link 19881003 Disease Relevance 0 Pain Relevance 0
However, both groups demonstrated a symmetrical side-to-side change in TrA and IO muscle thickness despite the symptomatic group having unilateral symptoms.
Regulation (change) of TrA in TrA
7) Confidence 0.16 Published 2009 Journal J Orthop Sports Phys Ther Section Body Doc Link 19881003 Disease Relevance 0 Pain Relevance 0
Further, we detected a preferential change in TrA muscle thickness during the ADIM in both groups.


Regulation (change) of TrA in muscle
8) Confidence 0.16 Published 2009 Journal J Orthop Sports Phys Ther Section Body Doc Link 19881003 Disease Relevance 0 Pain Relevance 0
Interestingly, skin sensitization did not change TR IIa (t(15) = 1, p = 0.357), but significantly attenuated the power decrease of the TR IIb (t(15) = 2.5; p = 0.024; ?
Neg (not) Regulation (change) of TR IIa in skin
9) Confidence 0.14 Published 2009 Journal Journal of pain research Section Body Doc Link PMC3004625 Disease Relevance 0.05 Pain Relevance 0.37
These findings suggest that respiratory modulation of TrA thickness, as measured by ultrasound imaging, greater than 20%, detected in a resting supine position, may be associated with an episode of hypocapnia, and if present warrants further investigation.
Regulation (modulation) of TrA in TrA associated with hypocapnia and imagery
10) Confidence 0.13 Published 2008 Journal Man Ther Section Abstract Doc Link 17544826 Disease Relevance 1.00 Pain Relevance 0.84
CONCLUSIONS: This study reinforces evidence for changes in automatic control of TrA in people with LBP.
Regulation (control) of TrA in TrA
11) Confidence 0.03 Published 2004 Journal Spine Section Body Doc Link 15543074 Disease Relevance 0 Pain Relevance 0
CONCLUSIONS: The population approach characterized the EK parameters and identified the low KM enzyme responsible for phenacetin O-deethylation as CYP1A2.
Regulation (responsible) of KM enzyme
12) Confidence 0.03 Published 2000 Journal Pharm. Res. Section Body Doc Link 11303964 Disease Relevance 0 Pain Relevance 0
We hypothesize that when exposed to thyroid hormone, sensitivity of thyroid hormone receptor (TR) isomers TR?
Regulation (sensitivity) of TR in thyroid associated with tricuspid valve insufficiency
13) Confidence 0.03 Published 2010 Journal Korean Circulation Journal Section Body Doc Link PMC2893366 Disease Relevance 1.66 Pain Relevance 0
Maladaptive motor control of the TrA and multifidus may also be related to other mechanisms such as alerted posture, muscle imbalance, pain and the development of a sedentary lifestyle.
Regulation (control) of TrA in TrA associated with pain
14) Confidence 0.03 Published 2004 Journal International Journal of Medical Sciences Section Body Doc Link PMC1074712 Disease Relevance 0.60 Pain Relevance 0.37
The differences between the preoperative dh and tr values and the follow-up values for the adjacent segments compared between rigid vs. non-rigid technique as for instrumented vs. non-instrumented technique are small, indicating an, if at all, minor influence of the operation strategy on the result.
Regulation (values) of tr
15) Confidence 0.02 Published 2003 Journal German Medical Science : GMS e-journal Section Body Doc Link PMC2703223 Disease Relevance 0.09 Pain Relevance 0
Analysis of glycoprotein M(matrix protein) by SVMProt shows that it may be a transmembrane region protein, participates in Type II (general) secretory pathway (IISP) and isomerase type intramolecular oxidoreductase activities.
Regulation (participates) of oxidoreductase
16) Confidence 0.01 Published 2008 Journal Bioinformation Section Body Doc Link PMC2586131 Disease Relevance 0.31 Pain Relevance 0
Importantly, SMT increased the activity of the oblique abdominal muscles with no change in the deep trunk muscle TrA, which is often the target of exercise interventions.
Neg (no) Regulation (change) of TrA in muscles
17) Confidence 0.01 Published 2007 Journal Man Ther Section Abstract Doc Link 17452118 Disease Relevance 0.59 Pain Relevance 0.42
Further examination of the protective action of flupirtine and retigabine against L-glutamate toxicity showed that it had no influence on monoamine oxidase (monoamine: oxygen oxidoreductase (deaminating), EC 1.4.3.4., MAO) activity.
Neg (no) Regulation (influence) of oxygen oxidoreductase associated with toxicity, glutamate and monoamine
18) Confidence 0.00 Published 2000 Journal Eur. J. Pharmacol. Section Abstract Doc Link 10988329 Disease Relevance 0.89 Pain Relevance 0.54

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