INT339510

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4) nucleus (Socs1) plasma membrane (Tlr4)
intracellular (Tlr4) cytoplasm (Tlr4)
Anatomy Link Frequency
proximal 1
Tlr4 (Mus musculus)
Socs1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 8 98.72 Very High Very High Very High
cytokine 5 98.04 Very High Very High Very High
tolerance 42 83.28 Quite High
agonist 3 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 9 98.72 Very High Very High Very High
Sepsis 10 5.00 Very Low Very Low Very Low
Infection 5 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Bacterial Infection 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In particular, SOCS-1 is upregulated by LPS and has been reported to catalyze the destruction of proximal elements of TLR signal complexes (31).
LPS Positive_regulation (upregulated) of SOCS-1 in proximal
1) Confidence 0.06 Published 2010 Journal mBio Section Body Doc Link PMC2962435 Disease Relevance 0.10 Pain Relevance 0.18

General Comments

This test has worked.

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