INT339512

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tlr4, Traf6) signal transduction (Tlr4, Traf6) plasma membrane (Tlr4, Traf6)
intracellular (Tlr4) protein complex assembly (Traf6) protein complex (Traf6)
Tlr4 (Mus musculus)
Traf6 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 42 94.20 High High
Inflammation 8 61.08 Quite High
cytokine 5 56.00 Quite High
agonist 3 43.04 Quite Low
palliative 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 9 61.08 Quite High
Infection 5 50.48 Quite High
Sepsis 10 46.92 Quite Low
Disease 2 34.56 Quite Low
Necrosis 1 18.40 Low Low
Cancer 1 18.04 Low Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Bacterial Infection 1 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IRAK-M is a catalytically inactive member of the IRAK kinase family that prevents formation of IRAK-1–TRAF6 complexes downstream of TLR4 (15, 16).
Negative_regulation (prevents) of TLR4 Binding (complexes) of TRAF6
1) Confidence 0.05 Published 2010 Journal mBio Section Body Doc Link PMC2962435 Disease Relevance 0.17 Pain Relevance 0.38

General Comments

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