INT339513

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.07
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Socs1, Eif2ak2) RNA binding (Eif2ak2) intracellular (Eif2ak2)
translation (Eif2ak2) kinase activity (Eif2ak2)
Socs1 (Mus musculus)
Eif2ak2 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 84 82.00 Quite High
Inflammation 16 66.12 Quite High
cytokine 10 65.44 Quite High
agonist 6 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 18 66.12 Quite High
Targeted Disruption 6 37.52 Quite Low
Sepsis 20 5.00 Very Low Very Low Very Low
Infection 10 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Bacterial Infection 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We therefore investigated the possibility that PKR and SOCS-1 interact functionally in vitro, resulting in K48 Ub of PKR.
SOCS-1 Binding (interact) of PKR
1) Confidence 0.04 Published 2010 Journal mBio Section Body Doc Link PMC2962435 Disease Relevance 0.07 Pain Relevance 0.15
Since the effects of SOCS-1 on PKR protein levels may be the result of regulation of an intermediate element, we evaluated the potential for SOCS-1 and PKR to interact physically in our overexpression system.
SOCS-1 Binding (interact) of PKR
2) Confidence 0.04 Published 2010 Journal mBio Section Body Doc Link PMC2962435 Disease Relevance 0 Pain Relevance 0

General Comments

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