INT339516

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Eif2ak2, TIRAP) protein binding, bridging (TIRAP) cytoplasm (TIRAP)
RNA binding (Eif2ak2) nucleus (Eif2ak2) plasma membrane (TIRAP)
Eif2ak2 (Mus musculus)
TIRAP (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 1 98.80 Very High Very High Very High
tolerance 42 90.40 High High
palliative 1 54.16 Quite High
Inflammation 8 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sepsis 10 67.00 Quite High
Stress 1 65.36 Quite High
Targeted Disruption 3 17.72 Low Low
INFLAMMATION 9 5.00 Very Low Very Low Very Low
Infection 5 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Bacterial Infection 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Specifically, PKR was shown to interact directly with the TLR4 adapter TIRAP/Mal and to exhibit a partial dependence on MyD88 for activation through TLR4 (24).
PKR Spec (partial) Binding (interact) of TIRAP associated with addiction
1) Confidence 0.25 Published 2010 Journal mBio Section Body Doc Link PMC2962435 Disease Relevance 0.19 Pain Relevance 0.23

General Comments

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