INT339533

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (VEGFA) small molecule metabolic process (CYP2C8) growth (VEGFA)
extracellular region (VEGFA) endoplasmic reticulum (CYP2C8) proteinaceous extracellular matrix (VEGFA)
Anatomy Link Frequency
endothelial cells 2
VEGFA (Homo sapiens)
CYP2C8 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 8 93.36 High High
Inflammation 33 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Taxol 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 1 94.16 High High
Cancer 116 92.52 High High
Hypoxia 4 81.60 Quite High
Apoptosis 2 34.68 Quite Low
INFLAMMATION 33 5.00 Very Low Very Low Very Low
Prostate Cancer 7 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Glioblastoma 4 5.00 Very Low Very Low Very Low
Metastasis 3 5.00 Very Low Very Low Very Low
Carcinoma 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In turn, VEGF can increase CYP2C promoter activity in endothelial cells and induce the expression of CYP2C8, resulting in increased intracellular EET levels [115].
VEGF Positive_regulation (induce) of Gene_expression (expression) of CYP2C8 in endothelial cells
1) Confidence 0.09 Published 2010 Journal Cancer Metastasis Rev Section Body Doc Link PMC2962793 Disease Relevance 0.57 Pain Relevance 0.09

General Comments

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