INT339592

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.26
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.27
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ARMS2) cytoplasm (ARMS2)
ARMS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 27 43.16 Quite Low
cva 18 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Nicotine 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
interneuron 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Age-related Macular Degeneration 309 99.84 Very High Very High Very High
Stress 4 96.52 Very High Very High Very High
Genetic Predisposition To Disease 2 91.76 High High
Nicotine Addiction 14 81.52 Quite High
Ocular Toxicity (including Many Sub-types) 62 68.60 Quite High
Diabetes Mellitus 2 50.44 Quite High
Hyperopia 1 46.36 Quite Low
Atherosclerosis 1 45.76 Quite Low
Obesity 2 43.84 Quite Low
Disease 66 43.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Schmidt and colleagues identified a coding change [Ala69Ser] in the LOC387715/ARMS2 gene on chromosome 10q26 as the second major identified susceptibility allele [123].
Regulation (change) of ARMS2
1) Confidence 0.26 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2962903 Disease Relevance 0.97 Pain Relevance 0
A more recent study suggests that the SNP in the LOC387715 (ARMS2) gene has direct effects on AMD risk presumably by affecting protein function, whereas the SNP in HTRA1 may be through an indirect pathway (Kanda et al. 2007).
Regulation (effects) of ARMS2 associated with age-related macular degeneration
2) Confidence 0.05 Published 2007 Journal Core Evidence Section Body Doc Link PMC3012443 Disease Relevance 1.30 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox