INT339596

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Context Info
Confidence 0.26
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (KLF4) nucleus (KLF4) intracellular (KLF4)
DNA binding (KLF4)
Anatomy Link Frequency
fibroblasts 1
KLF4 (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
interneuron 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retinal Diseases 11 49.76 Quite Low
Age-related Macular Degeneration 64 23.52 Low Low
Retina Disease 17 23.20 Low Low
Disease 56 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 14 5.00 Very Low Very Low Very Low
Leber Congenital Amaurosis /

Leber Congenital Amaurosis

5 5.00 Very Low Very Low Very Low
Aging 4 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Frailty 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This work was soon supplemented by the generation of human iPSCs by two groups, one of whom [186] showed that adult human dermal fibroblasts can also be reprogrammed by overexpression of OCT4, SOX2, KLF4, and c-MYC, while another [188] made use of a slightly different set of factors (OCT4, SOX2, LIN28, and NANOG) to reprogram both fetal and adult human fibroblasts.
Localization (generation) of KLF4 in fibroblasts
1) Confidence 0.26 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2962903 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

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