INT339670

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Context Info
Confidence 0.24
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

embryo development (Acvr1) kinase activity (Acvr1)
Anatomy Link Frequency
embryos 1
Acvr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrodysplasia Ossificans Progressiva 17 99.56 Very High Very High Very High
Heterotopic Ossification 87 97.68 Very High Very High Very High
Calcification 3 47.96 Quite Low
Targeted Disruption 12 15.92 Low Low
Injury 15 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Frailty 4 5.00 Very Low Very Low Very Low
Brain Injury 3 5.00 Very Low Very Low Very Low
Respiratory Failure 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, introducing a constitutively active ACVR1 mutation into zebrafish embryos failed to induce obvious HO even though strong ventralization due to enhanced BMP signaling was observed [20].
Positive_regulation (introducing) of ACVR1 in embryos associated with heterotopic ossification
1) Confidence 0.24 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2963134 Disease Relevance 0.47 Pain Relevance 0

General Comments

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