INT339743

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.39
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (SORBS1) cytoplasm (SORBS1) cytosol (SORBS1)
cytoskeletal protein binding (SORBS1) nucleolus (SORBS1) nucleus (SORBS1)
SORBS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 66 50.00 Quite Low
cytokine 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Bile 4 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 86 71.52 Quite High
Hepatocellular Cancer 16 55.68 Quite High
Osteogenic Sarcomas 2 28.28 Quite Low
Death 6 22.80 Low Low
Stress 8 21.68 Low Low
Diabetes Mellitus 44 5.00 Very Low Very Low Very Low
Toxicity 20 5.00 Very Low Very Low Very Low
Hepatotoxicity 18 5.00 Very Low Very Low Very Low
Apoptosis 16 5.00 Very Low Very Low Very Low
Insulin Resistance 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, pepck, pyruvate dehydrogenase kinase 4 (Pdk4) and c-Cbl-associated protein (Cap) were activated by the three compounds but with different time-curves, suggesting different mechanisms of gene regulation.
Positive_regulation (activated) of Cap
1) Confidence 0.06 Published 2010 Journal PPAR Research Section Body Doc Link PMC2963138 Disease Relevance 0.19 Pain Relevance 0
For example, pepck, pyruvate dehydrogenase kinase 4 (Pdk4) and c-Cbl-associated protein (Cap) were activated by the three compounds but with different time-curves, suggesting different mechanisms of gene regulation.
Positive_regulation (activated) of c-Cbl-associated protein
2) Confidence 0.06 Published 2010 Journal PPAR Research Section Body Doc Link PMC2963138 Disease Relevance 0.20 Pain Relevance 0

General Comments

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