INT33977

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Context Info
Confidence 0.00
First Reported 1986
Last Reported 1986
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (DIO2, PCDHB17) small molecule metabolic process (DIO2) cell adhesion (PCDHB17)
cellular nitrogen compound metabolic process (DIO2)
Anatomy Link Frequency
pituitary 1
DIO2 (Homo sapiens)
PCDHB17 (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 3 99.68 Very High Very High Very High
Opioid 1 99.06 Very High Very High Very High
Disease Link Frequency Relevance Heat
Syndrome 3 93.44 High High
Disease 4 92.64 High High
Adenoma 2 91.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To further elucidate the site of action of opioids on the pituitary-adrenal axis, we studied the effect of D-Ala2,MePhe4,met-(O)enkephalin-ol (Sandoz, FK 33-824) on plasma ACTH and beta-endorphin immunoreactivity and serum cortisol in 7 normal subjects and 11 patients with Cushing's syndrome (Cushing's disease, n = 7; adrenal adenoma, n = 2; ectopic Cushing's syndrome, n = 2) after administration of human corticotropin-releasing hormone (hCRH). hCRH (0.1 mg; Bachem) was injected iv after pretreatment with 0.5 mg FK 33-824, im, or 0.9% saline.
D-Ala2 Regulation (effect) of MePhe4 in pituitary associated with adenoma, syndrome, enkephalin, disease and opioid
1) Confidence 0.00 Published 1986 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 3023423 Disease Relevance 0.44 Pain Relevance 0.27

General Comments

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