INT339979

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Context Info
Confidence 0.02
First Reported 2011
Last Reported 2011
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (PRDX2, HDAC9) mitochondrion (PRDX2) oxidoreductase activity (PRDX2)
nucleus (HDAC9) transcription factor binding (HDAC9)
PRDX2 (Homo sapiens)
HDAC9 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 1 90.88 High High
Chronic pancreatitis 3 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fungal Infection 1 100.00 Very High Very High Very High
Thyroid Neoplasm 2 61.24 Quite High
Cancer 45 50.00 Quite Low
Disease 4 50.00 Quite Low
Death 14 29.84 Quite Low
Apoptosis 19 29.28 Quite Low
Repression 3 25.52 Quite Low
Pancreatic Cancer 24 5.00 Very Low Very Low Very Low
Adenocarcinoma 10 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Trichostatin (TSA), a fermentation product of Streptomyces, originally used as an antifungal agent, was found to have anticancer cells proliferation activity and the ability to inhibit HDAC with an IC50 in the nanomolar range [8].
TSA Neg (inhibit) Binding (inhibit) of HDAC associated with fungal infection
1) Confidence 0.02 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2964042 Disease Relevance 0.16 Pain Relevance 0.05

General Comments

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