INT340116

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

phosphatase activity (Dusp1) nucleoplasm (Dusp1) signal transduction (Oprm1)
plasma membrane (Oprm1) nucleus (Dusp1) cell cycle (Dusp1)
Dusp1 (Mus musculus)
Oprm1 (Mus musculus)
Oprm1 - A118G (1)
Pain Link Frequency Relevance Heat
Pain 91 100.00 Very High Very High Very High
Lasting pain 23 92.56 High High
Opioid 6 74.08 Quite High
depression 4 34.48 Quite Low
Pain threshold 9 5.00 Very Low Very Low Very Low
Chronic low back pain 3 5.00 Very Low Very Low Very Low
Endogenous opioid 2 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 119 100.00 Very High Very High Very High
Nociception 7 92.64 High High
Depressive Disorder 1 40.48 Quite Low
Depression 5 34.48 Quite Low
Low Back Pain 5 5.00 Very Low Very Low Very Low
Shock 2 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low
Somatoform Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similar to COMT Val158Met and BDNF Val66Met, no main effect of the OPRM1 A118G polymorphism on the pain ERP was apparent.
ERP Neg (no) Regulation (effect) of Transcription (polymorphism) of OPRM1 (A118G) associated with pain
1) Confidence 0.12 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2964315 Disease Relevance 0.71 Pain Relevance 0.69

General Comments

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