INT340117

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.48
Pain Relevance 2.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bdnf) cytoplasmic membrane-bounded vesicle (Bdnf)
Bdnf (Mus musculus)
Pain1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 182 100.00 Very High Very High Very High
Chronic low back pain 6 99.16 Very High Very High Very High
Lasting pain 46 98.54 Very High Very High Very High
Opioid 12 68.08 Quite High
Pain threshold 18 32.96 Quite Low
depression 8 25.04 Quite Low
Endogenous opioid 4 5.00 Very Low Very Low Very Low
backache 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 238 100.00 Very High Very High Very High
Low Back Pain 10 98.84 Very High Very High Very High
Nociception 14 30.72 Quite Low
Depression 10 25.04 Quite Low
Depressive Disorder 2 8.08 Low Low
Shock 4 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Somatoform Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similar to the results of the COMT polymorphism, the interaction between pain status and the BDNF Met allele indicated that when chronic low back pain complaints were present, the Met allele carriers displayed stronger ERP amplitudes (P1 component) compared to Val homozygotes.
BDNF Met allele Binding (interaction) of pain associated with low back pain, chronic low back pain and pain
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2964315 Disease Relevance 1.54 Pain Relevance 1.61
Analyses investigating the moderating effect of chronic pain complaints on the effect of the BDNF Met allele, revealed a significant interaction between pain status and the BDNF Met allele in the model of the P1- component of Fz (B?
BDNF Met allele Binding (interaction) of pain associated with pain and lasting pain
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2964315 Disease Relevance 0.94 Pain Relevance 0.94

General Comments

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