INT340369

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.04
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Tal (Mus musculus)
Pain Link Frequency Relevance Heat
Sicca syndrome 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 50 96.56 Very High Very High Very High
Nephrocalcinosis 14 95.20 Very High Very High Very High
Kidney Stones 41 94.24 High High
Sprains And Strains 3 87.48 High High
Cystinosis 2 67.40 Quite High
Lysosome Storage Disease 1 66.52 Quite High
Stress 1 52.28 Quite High
Dent Disease 19 5.00 Very Low Very Low Very Low
Proteinuria 16 5.00 Very Low Very Low Very Low
Cerebellooculorenal Syndrome 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The hypercalciuria observed in patients with Dent's disease and some ClC-5-deficient mice may be secondary to the PT dysfunction (urinary loss of vitamin D binding protein and reduced phosphate absorption, leading to increased 1,25(OH)2-vitamin D3 synthesis) or, at least in part, caused by the functional loss of ClC-5 in the TAL.
Negative_regulation (loss) of TAL associated with disease and kidney stones
1) Confidence 0.09 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2964617 Disease Relevance 1.04 Pain Relevance 0

General Comments

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