INT340421

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Il1a) extracellular space (Il1a) extracellular region (Il1a)
Golgi apparatus (Csk) plasma membrane (Csk) cytoplasm (Csk)
Il1a (Rattus norvegicus)
Csk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 1 90.92 High High
nMDA receptor 1 83.44 Quite High
chemokine 7 66.36 Quite High
Inflammation 9 38.72 Quite Low
cytokine 9 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
adenocard 4 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Status Epilepticus 106 96.40 Very High Very High Very High
Convulsion 10 88.20 High High
Death 6 84.40 Quite High
Drug Induced Neurotoxicity 1 71.12 Quite High
Injury 3 65.20 Quite High
INFLAMMATION 11 38.72 Quite Low
Brain Injury 3 35.68 Quite Low
Pressure And Volume Under Development 3 12.96 Low Low
Urological Neuroanatomy 14 5.00 Very Low Very Low Very Low
Epilepsy 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
increases N-methyl-D-aspartate (NMDA) receptor activity through IL-1RI-mediated activation of Src kinase family-mediated tyrosine phosphorylation of NR2A/B, which results in increased intracellular Ca2+ through an increase of its channel gating properties [74,79].
IL-1RI-mediated Positive_regulation (activation) of Src kinase
1) Confidence 0.00 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2964655 Disease Relevance 0.98 Pain Relevance 0.12

General Comments

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