INT340596

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Context Info
Confidence 0.51
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.38
Pain Relevance 1.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular matrix organization (Wnt3a) extracellular space (Wnt3a) extracellular region (Wnt3a)
proteinaceous extracellular matrix (Wnt3a) plasma membrane (Wnt3a) molecular_function (Wnt3a)
Wnt3a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fluoxetine 132 99.82 Very High Very High Very High
sSRI 10 78.08 Quite High
Serotonin 6 19.16 Low Low
depression 10 5.00 Very Low Very Low Very Low
antidepressant 10 5.00 Very Low Very Low Very Low
Hippocampus 6 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Intracerebroventricular 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 38 99.12 Very High Very High Very High
Targeted Disruption 8 82.44 Quite High
Depression 10 5.00 Very Low Very Low Very Low
Hypersensitivity 10 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Volume Depletion And Dehydration 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, it did not prevent increased Wnt3a expression, suggesting that the latter is not a sufficient event for increased progenitor cell mitosis.
Negative_regulation (prevent) of Gene_expression (expression) of Wnt3a
1) Confidence 0.51 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965105 Disease Relevance 0.38 Pain Relevance 0.48
However, adding K252a to fluoxetine did not prevent the latter's stimulating effect on Wnt3a expression (Figure 1D).
Negative_regulation (prevent) of Gene_expression (expression) of Wnt3a associated with fluoxetine
2) Confidence 0.38 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965105 Disease Relevance 0 Pain Relevance 0.92

General Comments

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