INT340730

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 7
Disease Relevance 6.67
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
lung 2
Gma3 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 7 91.60 High High
cytokine 14 86.80 High High
Inflammation 14 85.36 High High
tolerance 7 49.84 Quite Low
rheumatoid arthritis 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 392 100.00 Very High Very High Very High
Melanoma 77 100.00 Very High Very High Very High
Breast Cancer 56 100.00 Very High Very High Very High
Non-small-cell Lung Cancer 49 99.62 Very High Very High Very High
Solid Tumor 7 99.36 Very High Very High Very High
Lung Cancer 28 99.12 Very High Very High Very High
Erythema 14 98.08 Very High Very High Very High
Toxicity 63 95.32 Very High Very High Very High
Wilms Tumor 28 92.32 High High
Pain 7 91.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
van Cruijsen et al. [35] assessed the possible association of NGcGM3 expression with angiogenesis in lung cancer.
Gene_expression (expression) of NGcGM3 in lung associated with lung cancer
1) Confidence 0.01 Published 2010 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2965427 Disease Relevance 0.96 Pain Relevance 0.03
The ganglioside NGcGM3 has been described in human neoplasms, including breast carcinoma [33, 34] and melanoma [31], but is usually not detected in normal human cells.
Neg (not) Gene_expression (detected) of NGcGM3 associated with melanoma, cancer and breast cancer
2) Confidence 0.01 Published 2010 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2965427 Disease Relevance 1.56 Pain Relevance 0.04
Microvessel density, as determined by CD34 staining, was lower in NSCLC tissues with high NGcGM3 expression, suggesting that the presence of the ganglioside may favor an antiangiogenic response.
Gene_expression (expression) of NGcGM3 associated with non-small-cell lung cancer
3) Confidence 0.01 Published 2010 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2965427 Disease Relevance 1.00 Pain Relevance 0
They examined 176 samples of nonsmall cell lung cancer (NSCLC) by immunohistochemistry in tissue microarray and found that NGcGM3 is widely expressed in more than 90% of the cases.
Gene_expression (expressed) of NGcGM3 in lung associated with non-small-cell lung cancer
4) Confidence 0.01 Published 2010 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2965427 Disease Relevance 1.06 Pain Relevance 0
It is noteworthy that the monosialic acid ganglioside NGcGM3 is highly expressed in several human cancer cells [16].
Gene_expression (expressed) of NGcGM3 associated with cancer
5) Confidence 0.01 Published 2010 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2965427 Disease Relevance 0.31 Pain Relevance 0
More recently, Scursoni et al. [36] reported for the first time the expression of NGcGM3 in a pediatric solid tumor.
Gene_expression (expression) of NGcGM3 associated with solid tumor
6) Confidence 0.01 Published 2010 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2965427 Disease Relevance 0.92 Pain Relevance 0
The main toxicities observed in stage III/IV breast cancer patients receiving the NGcGM3/VSSP vaccine (200??
Gene_expression (vaccine) of NGcGM3 associated with breast cancer
7) Confidence 0.00 Published 2010 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2965427 Disease Relevance 0.86 Pain Relevance 0.14

General Comments

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