INT340755

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.08
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CARTPT) extracellular space (CARTPT) extracellular region (CARTPT)
molecular_function (CARTPT) cell-cell signaling (CARTPT)
Anatomy Link Frequency
plasma 1
CARTPT (Homo sapiens)
Pain Link Frequency Relevance Heat
cocaine 1 89.72 High High
Neuropeptide 2 89.40 High High
Inflammation 8 85.00 Quite High
Neurotransmitter 3 62.16 Quite High
Central nervous system 14 61.64 Quite High
Pain 1 59.92 Quite High
substance P 1 55.80 Quite High
Enkephalin 1 55.16 Quite High
Inflammatory marker 1 45.20 Quite Low
Glutamate 1 22.00 Low Low
Disease Link Frequency Relevance Heat
Disease 128 99.40 Very High Very High Very High
Parkinson's Disease 155 98.12 Very High Very High Very High
INFLAMMATION 9 85.00 Quite High
Meningitis 4 83.96 Quite High
Disease Progression 4 83.76 Quite High
Syndrome 9 82.60 Quite High
Dementia 73 82.24 Quite High
Frailty 3 77.92 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 55 77.44 Quite High
Pain 1 59.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The depletion of CART may be a causative factor in the dysfunction of the dopaminergic system seen in DLB.
Negative_regulation (depletion) of CART associated with parkinson's disease
1) Confidence 0.30 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2965495 Disease Relevance 1.56 Pain Relevance 0.33
A related observation was the increase of anti-MOG antibodies in the early samples after initiation of cART despite decrease of the plasma and (to a lesser extent) CSF viral load.
Negative_regulation (initiation) of cART in plasma
2) Confidence 0.07 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2998475 Disease Relevance 0.52 Pain Relevance 0.07

General Comments

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