INT340794

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Context Info
Confidence 0.65
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 4.50
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Btla (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 24 87.36 High High
Inflammation 45 86.56 High High
corticosteroid 3 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 60 100.00 Very High Very High Very High
Cold Sores 159 99.32 Very High Very High Very High
Infection 117 99.08 Very High Very High Very High
Keratitis 111 98.60 Very High Very High Very High
INFLAMMATION 51 86.56 High High
Disease 24 54.16 Quite High
Herpes Simplex Virus Infection 9 50.00 Quite Low
Keloid Scars 3 40.08 Quite Low
Pressure And Volume Under Development 24 5.00 Very Low Very Low Very Low
Sprains And Strains 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, pBTLA treated mice showed a reduced DTH response two weeks after HSV-1 infection compared to pcDNA or PBS treated mice.
Localization (response) of pBTLA associated with cold sores, hypersensitivity and infection
1) Confidence 0.65 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 1.91 Pain Relevance 0.17
concentrations were reduced in splenocytes isolated from pBTLA treated mice when stimulated in vitro, indicating that pBTLA treated mice had a reduced Th1 immune response.
Localization (response) of pBTLA
2) Confidence 0.65 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 1.36 Pain Relevance 0.13
Comparison of the gD and BTLA binding sites on HVEM shows that the BTLA and gD binding sites are largely overlapping and involve similar structural motifs as well as similar energetics [12,40].
Localization (sites) of BTLA
3) Confidence 0.33 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 1.22 Pain Relevance 0.03

General Comments

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