INT340796

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 4.64
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Ly6g6d) molecular_function (Ly6g6d) cellular_component (Ly6g6d)
biological_process (Ly6g6d)
Anatomy Link Frequency
T cells 1
Ly6g6d (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 24 92.92 High High
Inflammation 45 67.40 Quite High
corticosteroid 3 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cold Sores 159 99.32 Very High Very High Very High
Infection 117 96.52 Very High Very High Very High
Hypersensitivity 60 85.88 High High
Keratitis 111 82.92 Quite High
INFLAMMATION 51 67.40 Quite High
Herpes Simplex Virus Infection 9 50.00 Quite Low
Keloid Scars 3 39.60 Quite Low
Disease 24 12.28 Low Low
Pressure And Volume Under Development 24 5.00 Very Low Very Low Very Low
Sprains And Strains 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transfer of HSV to T cells depends mainly on the binding of gD to its receptor, HVEM [36]. gD is expressed on the surface of activated T cells after infection [37].
gD Binding (binding) of in T cells associated with cold sores and infection
1) Confidence 0.04 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 1.57 Pain Relevance 0.12
Comparison of the gD and BTLA binding sites on HVEM shows that the BTLA and gD binding sites are largely overlapping and involve similar structural motifs as well as similar energetics [12,40].
gD Binding (binding) of
2) Confidence 0.03 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 1.16 Pain Relevance 0.03
The entry of HSV-1 into cells is well known to require membrane fusion between the virus envelope and cell membrane, which is primarily mediated by the interaction of the viral ligand, glycoprotein D(gD)and its cellular receptor HVEM [33-35].
gD Binding (interaction) of associated with cold sores
3) Confidence 0.03 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 1.91 Pain Relevance 0.15

General Comments

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