INT340801

Context Info Confidence 0.37 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 3 Disease Relevance 2.70 Pain Relevance 0.27

Anatomy Link Frequency corneas 2 Btla (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 45 82.40 Inflammatory response 3 81.44 cytokine 24 5.00 corticosteroid 3 5.00 cINOD 3 5.00 imagery 3 5.00

Disease Link Frequency Relevance Heat Eye Disease 6 99.96 Hypersensitivity 60 99.44 Cold Sores 159 99.00 Infection 117 98.76 Viral Infection 3 90.88 Corneal Opacity 12 87.08 Keratitis 111 84.20 INFLAMMATION 51 82.40 Pressure And Volume Under Development 24 70.08 Herpes Simplex Virus Infection 9 50.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Treatment with pBTLA decreases ocular disease severity

Negative_regulation (decreases) of pBTLA Binding (Treatment) of associated with eye disease

1) Confidence 0.37 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 0.67 Pain Relevance 0.10

Treatment with pBTLA suppresses the systemic DTH responses of mice

Negative_regulation (suppresses) of pBTLA Binding (Treatment) of associated with hypersensitivity

2) Confidence 0.37 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 0.82 Pain Relevance 0.03

Treatment with pBTLA reduces CD4+ T cell response to HSV-1 infection in corneas

Negative_regulation (reduces) of pBTLA Binding (Treatment) of in corneas associated with cold sores and infection

3) Confidence 0.37 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 1.21 Pain Relevance 0.14

General Comments

This test has worked.