INT340812

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Context Info
Confidence 0.32
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 5.94
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
cornea 2
tear 1
Btla (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 90 99.20 Very High Very High Very High
Inflammatory response 6 80.64 Quite High
cytokine 48 66.52 Quite High
corticosteroid 6 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cold Sores 318 99.80 Very High Very High Very High
Eye Disease 12 99.56 Very High Very High Very High
INFLAMMATION 102 99.20 Very High Very High Very High
Hypersensitivity 120 99.00 Very High Very High Very High
Infection 234 98.44 Very High Very High Very High
Viral Infection 6 90.00 High High
Corneal Opacity 24 87.08 High High
Keratitis 222 84.20 Quite High
Pressure And Volume Under Development 48 69.44 Quite High
Herpes Simplex Virus 18 60.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treatment with pBTLA reduces CD4+ T cell response to HSV-1 infection in corneas
pBTLA Binding (Treatment) of in corneas associated with cold sores and infection
1) Confidence 0.32 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 1.20 Pain Relevance 0.14
Treatment with pBTLA does not affect virus titers in tear film
pBTLA Binding (Treatment) of in tear
2) Confidence 0.32 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 0.92 Pain Relevance 0.05
Treatment with pBTLA does not affect gD expression in cornea
pBTLA Binding (Treatment) of in cornea
3) Confidence 0.32 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 1.04 Pain Relevance 0.04
Treatment with pBTLA suppresses the systemic DTH responses of mice
pBTLA Binding (Treatment) of associated with hypersensitivity
4) Confidence 0.32 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 0.81 Pain Relevance 0.03
Treatment with pBTLA decreases ocular disease severity
pBTLA Binding (Treatment) of associated with eye disease
5) Confidence 0.32 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 0.67 Pain Relevance 0.10
Comparison of the gD and BTLA binding sites on HVEM shows that the BTLA and gD binding sites are largely overlapping and involve similar structural motifs as well as similar energetics [12,40].
BTLA Binding (binding) of
6) Confidence 0.32 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 1.29 Pain Relevance 0.03

General Comments

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