INT340828

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 5.17
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ADCY10) plasma membrane (ADCY10) cytoskeleton (ADCY10)
cytoplasm (ADCY10)
Anatomy Link Frequency
tear 2
band 1
ADCY10 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 16 95.80 Very High Very High Very High
tolerance 8 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Conjunctivitis 196 100.00 Very High Very High Very High
Heart Rate Under Development 152 99.80 Very High Very High Very High
Hypersensitivity 40 98.52 Very High Very High Very High
Eye Disease 16 97.28 Very High Very High Very High
INFLAMMATION 20 95.80 Very High Very High Very High
Conjunctiva Disease 148 95.76 Very High Very High Very High
Dry Eye 20 85.68 High High
Disease 28 74.00 Quite High
Sicca Syndrome 40 60.44 Quite High
Increased Venous Pressure Under Development 4 36.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our finding of increased sPLA2-IIa expression in SAC and PAC patients is in agreement with the study by Chen et al., which demonstrated that sPLA2-IIa is an inflammatory mediator when the ocular surface is compromised [21].
Regulation (finding) of SAC associated with heart rate under development, conjunctivitis and inflammation
1) Confidence 0.06 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965574 Disease Relevance 1.38 Pain Relevance 0.11
Investigations, including our current study, have documented the alteration of tear protein in SAC and PAC, explored the underlying pathogenic mechanisms of allergic eye disease, and extended our knowledge of the cellular and mediator mechanisms involved.
Regulation (alteration) of SAC in tear associated with heart rate under development, conjunctivitis, hypersensitivity and eye disease
2) Confidence 0.06 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965574 Disease Relevance 1.46 Pain Relevance 0
There is a significantly increased intensity of band 4 (serum protein), band 6 (Ig gamma-2), and band 9 (leukocyte elastase inhibitor) in SAC and PAC patients.
Regulation (intensity) of SAC in band associated with heart rate under development and conjunctivitis
3) Confidence 0.06 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965574 Disease Relevance 1.04 Pain Relevance 0
The tear protein changes in SAC and PAC patients may contribute to instability of tear film.



Regulation (changes) of SAC in tear associated with heart rate under development and conjunctivitis
4) Confidence 0.03 Published 2010 Journal Molecular Vision Section Abstract Doc Link PMC2965574 Disease Relevance 1.29 Pain Relevance 0

General Comments

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