INT340843

Context Info Confidence 0.02 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.24 Pain Relevance 0.80

plasma membrane (Cd24a)

Cd24a (Mus musculus)

Pain Link Frequency Relevance Heat diclofenac 140 100.00 cINOD 34 68.96 tolerance 1 5.48 aspirin 1 5.00 Bile 1 5.00 Inflammation 1 5.00 lumbar region 1 5.00

Disease Link Frequency Relevance Heat Hypersensitivity 28 98.96 Anaemia 1 90.28 Anaphylaxis 9 17.72 INFLAMMATION 3 5.00 Immunization 2 5.00 Disease 2 5.00 Urticaria 1 5.00 Emergencies 1 5.00 Adverse Drug Reaction 1 5.00 Respiratory Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Linkage of DF/DF-metabolites by their carboxyl groups (position 1) to HSA mimics a chemical modification of proteins via reactive acyl glucuronides, which is the most important mechanism of detoxification [10].

HSA Binding (Linkage) of associated with diclofenac

1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965666 Disease Relevance 0.24 Pain Relevance 0.80

General Comments

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