INT340879

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Context Info
Confidence 0.32
First Reported 2010
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.99
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cellular_component (Hspbp1)
Anatomy Link Frequency
striatum 1
cerebellum 1
Hspbp1 (Mus musculus)
Pain Link Frequency Relevance Heat
midbrain 24 57.92 Quite High
Hippocampus 12 5.00 Very Low Very Low Very Low
medulla 12 5.00 Very Low Very Low Very Low
cerebral cortex 6 5.00 Very Low Very Low Very Low
ischemia 6 5.00 Very Low Very Low Very Low
Thalamus 6 5.00 Very Low Very Low Very Low
Hsan 3 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
dopamine receptor 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 42 82.04 Quite High
Cancer 3 80.24 Quite High
Cataract 3 70.60 Quite High
Muscular Atrophy 3 53.28 Quite High
Embryonic Lethality 3 51.76 Quite High
Targeted Disruption 9 50.36 Quite High
Clinical Trials And Case Reports 3 50.00 Quite Low
Disease 30 5.00 Very Low Very Low Very Low
Stress 27 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hspbp1 is not inducible; it is highly expressed in the forebrain with lower levels in the cerebellum and striatum.
Neg (not) Positive_regulation (inducible) of Hspbp1 in striatum
1) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965669 Disease Relevance 0.45 Pain Relevance 0
One well-studied functional cluster of genes involved in the folding of cytosolic proteins includes Hspa8, a variety of DnaJs, nucleotide exchange factors Bag1 and Hspbp1 (releasing Hspa8 of ADP), and Hspabp, a stabilizing factor for ADP-bound Hspa8.
Positive_regulation (stabilizing) of Hspbp1
2) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965669 Disease Relevance 0.08 Pain Relevance 0.03
Hspbp1 is not inducible; it is highly expressed in the forebrain with lower levels in the cerebellum and striatum.
Neg (not) Positive_regulation (inducible) of Hspbp1 in cerebellum
3) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965669 Disease Relevance 0.45 Pain Relevance 0

General Comments

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