INT340924

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (PIK3CB, AKT1) cytosol (PIK3CB, AKT1) signal transduction (PIK3CB, AKT1)
nucleus (PIK3CB, AKT1) cell differentiation (AKT1) nucleoplasm (AKT1)
PIK3CB (Homo sapiens)
AKT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cerebral cortex 5 5.00 Very Low Very Low Very Low
Somatosensory cortex 4 5.00 Very Low Very Low Very Low
gABA 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
interneuron 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disseminated Intravascular Coagulation 10 5.00 Very Low Very Low Very Low
Malformations Of Cortical Development 7 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 6 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low
Schizophrenia 1 5.00 Very Low Very Low Very Low
Intellectual Impairment 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Autism 1 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To further assess the influence of intracellular reelin signaling, we used PP2 (10 ┬ÁM), a Src inhibitor, which blocks Dab1 phosphorylation, as well as LY294002, which by inhibiting PI3K prevents the activation of Akt.
PI3K Negative_regulation (prevents) of Positive_regulation (activation) of Akt
1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965671 Disease Relevance 0 Pain Relevance 0

General Comments

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