INT340991

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.20
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (VLDLR) transport (VLDLR) extracellular space (VLDLR)
plasma membrane (VLDLR) nucleus (VLDLR)
Anatomy Link Frequency
radial 2
VLDLR (Homo sapiens)
Pain Link Frequency Relevance Heat
cerebral cortex 20 5.00 Very Low Very Low Very Low
Somatosensory cortex 16 5.00 Very Low Very Low Very Low
gABA 12 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
interneuron 4 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disseminated Intravascular Coagulation 40 75.60 Quite High
Malformations Of Cortical Development 28 61.96 Quite High
Neurodegenerative Disease 24 5.00 Very Low Very Low Very Low
Epilepsy 4 5.00 Very Low Very Low Very Low
Syndrome 4 5.00 Very Low Very Low Very Low
Schizophrenia 4 5.00 Very Low Very Low Very Low
Intellectual Impairment 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Autism 4 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We further investigated the effects induced by reelin and found that signaling was mediated via VLDLR/Dab1/Pi3K activation while NRG1 signaling was mediated via erbB3/erbB4/Pi3K.
Positive_regulation (activation) of VLDLR
1) Confidence 0.08 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2965671 Disease Relevance 0.06 Pain Relevance 0
Reelin affects the number of radial glial processes expressing BLBP via VLDLR/Dab1/Pi3K activation
Positive_regulation (activation) of VLDLR in radial
2) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965671 Disease Relevance 0 Pain Relevance 0
The full length or the central fragment of reelin realigns disrupted radial glia via VLDLR/Dab1/Pi3K activation
Positive_regulation (activation) of VLDLR in radial
3) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965671 Disease Relevance 0.08 Pain Relevance 0
Activation of ApoER2, Dab1, and PI3K but not VLDLR and GSK3?
Positive_regulation (Activation) of VLDLR
4) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965671 Disease Relevance 0.06 Pain Relevance 0

General Comments

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