INT341235

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.24
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (INS) small molecule metabolic process (INS) extracellular region (INS)
nucleus (Eif4ebp1) carbohydrate metabolic process (INS) protein complex (Eif4ebp1)
INS (Homo sapiens)
Eif4ebp1 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 72 96.68 Very High Very High Very High
cerebral cortex 20 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 70 96.68 Very High Very High Very High
Stress 56 51.92 Quite High
Hypoxia 12 5.00 Very Low Very Low Very Low
Cancer 12 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 2 5.00 Very Low Very Low Very Low
Brain Disease 2 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Oxygen-glucose deprivation or insulin deprivation induced dephosphorylation of 4E-BP1 at Thr36/Thr45 and Ser64 residues in the ?
Negative_regulation (deprivation) of insulin Positive_regulation (induced) of Phosphorylation (dephosphorylation) of 4E-BP1
1) Confidence 0.01 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2966049 Disease Relevance 0.09 Pain Relevance 0.04
Insulin treatment of cells after deprivation is known to modify phosphorylation of 4E-BP1 at Thr36/Thr45 as the first event in cell lines (9, 23, 29, 37).
Negative_regulation (deprivation) of Insulin Positive_regulation (modify) of Phosphorylation (phosphorylation) of 4E-BP1
2) Confidence 0.01 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2966049 Disease Relevance 0.15 Pain Relevance 0.05

General Comments

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