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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.28
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnfrsf11b) extracellular space (Tnfrsf11b) extracellular region (Tnfrsf11b)
proteinaceous extracellular matrix (Tnfrsf11b) extracellular matrix organization (Tnfrsf11b)
Anatomy Link Frequency
osteoblast 1
Tnfrsf11b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nociceptor 3 83.84 Quite High
Cancer pain 22 82.96 Quite High
Pain 52 77.20 Quite High
Intractable pain 2 57.92 Quite High
imagery 30 50.00 Quite Low
positron emission tomography 15 31.80 Quite Low
Breakthrough pain 5 21.24 Low Low
Analgesic 6 21.12 Low Low
Pain management 1 11.04 Low Low
Spinal cord 20 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 7 99.98 Very High Very High Very High
Cancer 86 98.70 Very High Very High Very High
Hypercalcemia 2 89.44 High High
Bone Cancer 38 82.76 Quite High
Pain 59 77.20 Quite High
Disease 1 66.40 Quite High
Intractable Pain 2 57.92 Quite High
Aggression 3 53.24 Quite High
Metastasis 20 51.52 Quite High
Embolism 1 49.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The tumor releases osteoclast maturation factors or stimulates osteoblast secretion of RANKL and down-regulation of osteoprotegerin, resulting in dominant resorptive activity [9], [84], [85].
Localization (secretion) of osteoprotegerin in osteoblast associated with cancer and osteoporosis
1) Confidence 0.14 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2966439 Disease Relevance 1.28 Pain Relevance 0.45

General Comments

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