INT341309

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.04
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Npc1) nuclear envelope (Npc1) Golgi apparatus (Npc1)
endoplasmic reticulum (Npc1) plasma membrane (Npc1) lysosome (Npc1)
Npc1 (Mus musculus)
Sugt1 (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 8 98.68 Very High Very High Very High
Atherosclerosis 12 93.80 High High
Coronary Artery Disease 42 89.88 High High
Stress 2 86.48 High High
Apoptosis 3 85.20 High High
Necrosis 1 65.84 Quite High
Disorder Of Lipid Metabolism 7 62.32 Quite High
Nicotine Addiction 30 50.00 Quite Low
Hyperlipidemia 1 44.64 Quite Low
Diabetes Mellitus 9 43.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthormore, rs1805081 has been found to be associated with obesity[23] and Alzheimer's[24] while studies in mice suggest that the G allele is protective here and might be associated with NPC1 activity.
NPC1 Spec (might) Binding (associated) of allele associated with obesity
1) Confidence 0.01 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2966454 Disease Relevance 1.04 Pain Relevance 0

General Comments

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