INT341336

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 1.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Nav1) peptidase activity (Pepd) cytoskeleton (Nav1)
cytoplasm (Nav1)
Pepd (Mus musculus)
Nav1 (Mus musculus)
Pain Link Frequency Relevance Heat
nav1.7 47 100.00 Very High Very High Very High
Sodium channel 17 97.04 Very High Very High Very High
Pain 44 90.92 High High
Analgesic 3 82.76 Quite High
addiction 5 72.48 Quite High
action potential 5 53.44 Quite High
Analgesia congenital 3 5.00 Very Low Very Low Very Low
potassium channel 3 5.00 Very Low Very Low Very Low
pain insensitivity 1 5.00 Very Low Very Low Very Low
hsan 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Erythermalgia 12 100.00 Very High Very High Very High
Somatoform Disorder 10 100.00 Very High Very High Very High
Febrile Convulsions 3 99.84 Very High Very High Very High
Pain 46 90.92 High High
Nociception 1 20.80 Low Low
Injury 5 5.00 Very Low Very Low Very Low
Channelopathies 4 5.00 Very Low Very Low Very Low
Bites And Stings 3 5.00 Very Low Very Low Very Low
Polio 3 5.00 Very Low Very Low Very Low
Fever 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previously reported missense mutations in Nav1.7 have been associated with PE, PEPD or febrile seizures and are mostly located to cytoplasmic linkers of the sodium channel, with some PE causing mutations in transmembrane domains.
PEPD Binding (associated) of Nav1.7 associated with somatoform disorder, sodium channel, febrile convulsions, erythermalgia and nav1.7
1) Confidence 0.07 Published 2010 Journal Human Mutation Section Body Doc Link PMC2966863 Disease Relevance 0.92 Pain Relevance 1.30

General Comments

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