INT341371

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.99
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ephb1) signal transduction (Ephb1) plasma membrane (Ephb1)
nucleus (CRX) cytoplasm (Ephb1)
Anatomy Link Frequency
visceral 1
spinal cord 1
CRX (Homo sapiens)
Ephb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
amygdala 34 100.00 Very High Very High Very High
Visceral pain 9 99.64 Very High Very High Very High
anesthesia 10 97.16 Very High Very High Very High
Spinal cord 6 95.12 Very High Very High Very High
Dorsal horn 2 89.04 High High
imagery 1 74.96 Quite High
Thalamus 1 68.00 Quite High
Hippocampus 1 65.92 Quite High
cerebral cortex 2 53.36 Quite High
Somatic pain 1 40.24 Quite Low
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

24 100.00 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

9 99.64 Very High Very High Very High
Unconsciousness 4 80.80 Quite High
Pain 11 39.60 Quite Low
Anxiety Disorder 8 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Nociception 4 5.00 Very Low Very Low Very Low
Depression 4 5.00 Very Low Very Low Very Low
Post-traumatic Stress Disorder 3 5.00 Very Low Very Low Very Low
Hypersensitivity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The main result of this study is that the expression of CRF and pERK in the CeA was significantly increased by CRD-induced visceral pain, and that this effect was attenuated by general anesthesia, whereas the expression of c-Fos in the spinal cord was unaffected by general anesthesia.
CRD Positive_regulation (increased) of in spinal cord Gene_expression (expression) of pERK in visceral associated with anesthesia, visceral pain, amygdala and spinal cord
1) Confidence 0.02 Published 2010 Journal Journal of Korean Medical Science Section Body Doc Link PMC2967003 Disease Relevance 0.15 Pain Relevance 0.90

General Comments

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