INT341427

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Context Info
Confidence 0.52
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (EPO, BDNF) signal transduction (EPO) extracellular space (EPO)
aging (EPO) cytoplasmic membrane-bounded vesicle (BDNF)
Anatomy Link Frequency
nerve 1
EPO (Homo sapiens)
BDNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Nerve growth factor 3 99.80 Very High Very High Very High
Inflammation 2 98.24 Very High Very High Very High
antidepressant 24 94.00 High High
Hippocampus 2 89.52 High High
imagery 6 85.24 High High
Inflammatory marker 2 78.48 Quite High
depression 24 50.00 Quite Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 98.24 Very High Very High Very High
Cognitive Disorder 26 70.84 Quite High
Attention Deficit Hyperactivity Disorder 7 62.48 Quite High
Obesity 1 54.16 Quite High
Depression 22 50.00 Quite Low
Affective Disorder 15 45.60 Quite Low
Disorder Of Lipid Metabolism 1 34.08 Quite Low
Manic Depressive Disorder 16 5.00 Very Low Very Low Very Low
Aplasia 6 5.00 Very Low Very Low Very Low
Hypertension 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is known that Epo increase hippocampal BDNF and nerve growth factor (NGF) and has anti-inflammatory actions, but it is unclear whether these actions are mechanistically important for potential antidepressant effects of Epo.
Epo Positive_regulation (increase) of BDNF in nerve associated with antidepressant, inflammation and nerve growth factor
1) Confidence 0.52 Published 2010 Journal Trials Section Body Doc Link PMC2967509 Disease Relevance 0.36 Pain Relevance 0.48

General Comments

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