INT341488

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD8A, TLR2) signal transduction (TLR2) extracellular region (CD8A)
intracellular (TLR2) cytoplasm (TLR2)
Anatomy Link Frequency
NK cells 1
CD8A (Homo sapiens)
TLR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 7 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diffuse Cutaneous Leishmaniasis 74 100.00 Very High Very High Very High
Leishmaniasis 50 59.52 Quite High
Hypersensitivity 2 32.64 Quite Low
Infection 18 28.76 Quite Low
Cancer 1 9.96 Low Low
Apoptosis 17 5.00 Very Low Very Low Very Low
Disease 12 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low
Viral Infection 2 5.00 Very Low Very Low Very Low
Chronic Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
production in human NK cells [6], we therefore stimulated CD8 from DCL patients with LPG and also with Pam3Cys, a recognized specific TLR2 ligands (Figure 6A, B and C).
CD8 Binding (recognized) of TLR2 in NK cells associated with diffuse cutaneous leishmaniasis
1) Confidence 0.08 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2970528 Disease Relevance 0.31 Pain Relevance 0

General Comments

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