INT341502

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

chromosome organization (Apc) plasma membrane (Apc) nucleus (Apc)
protein complex assembly (Apc) cytoplasm (Apc)
Anatomy Link Frequency
T-cell 2
Apc (Mus musculus)
Pdcd1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 7 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diffuse Cutaneous Leishmaniasis 74 90.88 High High
Hypersensitivity 2 67.84 Quite High
Infection 18 63.96 Quite High
Cancer 1 45.16 Quite Low
Viral Infection 2 35.48 Quite Low
Disease 12 20.76 Low Low
Leishmaniasis 50 5.00 Very Low Very Low Very Low
Apoptosis 17 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low
Chronic Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
“Exhausted” cells have been shown to express higher levels of PD-1, among other inhibitors, and essays of restoration of these exhausted T-lymphocytes have focused on the use of anti-PD-L1 and PD-L2 antibodies, which prevent binding of T-cell PD-1 to the antigen-presenting cell (APC) ligands PD-L1 and PD-L2 [16], [17], [38].
Negative_regulation (prevent) of APC Binding (binding) of PD-1 in T-cell
1) Confidence 0.00 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2970528 Disease Relevance 0.53 Pain Relevance 0

General Comments

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