INT341507

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TLR2) plasma membrane (TLR2) intracellular (TLR2)
cytoplasm (TLR2)
TLR2 (Homo sapiens)
Pdcd1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 7 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diffuse Cutaneous Leishmaniasis 74 98.40 Very High Very High Very High
Hypersensitivity 2 45.24 Quite Low
Infection 18 41.36 Quite Low
Leishmaniasis 50 31.52 Quite Low
Cancer 1 22.56 Low Low
Viral Infection 2 12.88 Low Low
Apoptosis 17 5.00 Very Low Very Low Very Low
Disease 12 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low
Chronic Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we hypothesized that TLR2 stimulation could reduce PD-1 expression and restore CD8 functional activity in DCL patients against MOi.
Positive_regulation (stimulation) of TLR2 Negative_regulation (reduce) of Gene_expression (expression) of PD-1 associated with diffuse cutaneous leishmaniasis
1) Confidence 0.01 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2970528 Disease Relevance 0.30 Pain Relevance 0

General Comments

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