INT341535

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (THBS1) extracellular region (THBS1) cell adhesion (THBS1)
structural molecule activity (THBS1) Golgi apparatus (F2RL1) plasma membrane (F2RL1)
F2RL1 (Homo sapiens)
THBS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 35 72.40 Quite High
COX2 1 39.20 Quite Low
Arthritis 5 19.16 Low Low
Inflammatory response 3 6.60 Low Low
agonist 26 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Wound Healing 1 96.76 Very High Very High Very High
Cancer 20 89.32 High High
Disease 5 83.52 Quite High
Metastasis 4 76.00 Quite High
Thrombosis 1 72.76 Quite High
INFLAMMATION 42 72.40 Quite High
Chronic Obstructive Pulmonary Disease 2 24.44 Low Low
Multiple Sclerosis 1 23.84 Low Low
Renal Disease 1 20.52 Low Low
Arthritis 5 19.16 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previously, it was known to be only activated by PAR1, but now we suggest that PAR2 can also trigger expression of thrombospondin-1.


PAR2 Positive_regulation (trigger) of Gene_expression (expression) of thrombospondin-1
1) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2970545 Disease Relevance 0.75 Pain Relevance 0.04

General Comments

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