INT341538

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (F2, F2RL1) peptidase activity (F2) extracellular space (F2)
extracellular region (F2) Golgi apparatus (F2RL1) signal transducer activity (F2RL1)
F2 (Homo sapiens)
F2RL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 35 99.12 Very High Very High Very High
agonist 26 97.80 Very High Very High Very High
cytokine 3 58.48 Quite High
antagonist 4 45.08 Quite Low
Arthritis 5 32.80 Quite Low
fibrosis 1 17.44 Low Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 42 99.12 Very High Very High Very High
Cancer 20 91.76 High High
Metastasis 4 89.28 High High
Edema 1 65.68 Quite High
Adhesions 2 62.24 Quite High
Disease 5 47.00 Quite Low
Contact Dermatitis 1 41.76 Quite Low
Hypersensitivity 1 39.04 Quite Low
Arthritis 5 32.80 Quite Low
Cardiovascular Disease 1 24.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PAR2 is activated by mainly serine proteases (e.g. trypsin, tryptase, cathepsin G) but not thrombin and may be linked to inflammatory and proliferative disorders [4].
thrombin Positive_regulation (activated) of PAR2 associated with inflammation
1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2970545 Disease Relevance 0.68 Pain Relevance 0.24

General Comments

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