INT341540

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (F2RL1) plasma membrane (F2RL1) signal transducer activity (F2RL1)
Anatomy Link Frequency
kidney 3
F2RL1 (Homo sapiens)
AREG (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 26 24.24 Low Low
Inflammation 35 9.52 Low Low
Arthritis 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chronic Obstructive Pulmonary Disease 2 98.24 Very High Very High Very High
Cancer 20 89.04 High High
Metastasis 4 88.16 High High
Carcinoma 1 61.52 Quite High
Targeted Disruption 2 32.76 Quite Low
Breast Cancer 1 32.48 Quite Low
INFLAMMATION 42 9.52 Low Low
Arthritis 5 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our array data has demonstrated that amphiregulin expression is also substantially induced in kidney cells by PAR2 activation and this may be important in proliferation of kidney cells.


Positive_regulation (activation) of PAR2 in kidney Positive_regulation (induced) of Gene_expression (expression) of amphiregulin in kidney
1) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2970545 Disease Relevance 0.51 Pain Relevance 0

General Comments

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