INT341542

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.28
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (DUSP4, MAPK8) nucleus (DUSP4, MAPK8) cytosol (MAPK8)
mitochondrion (MAPK8) response to stress (MAPK8) cytoplasm (MAPK8)
DUSP4 (Homo sapiens)
MAPK8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 35 97.96 Very High Very High Very High
agonist 26 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 42 97.96 Very High Very High Very High
Metastasis 4 64.32 Quite High
Cancer 20 63.72 Quite High
Chronic Obstructive Pulmonary Disease 2 52.72 Quite High
Carcinoma 1 16.00 Low Low
Arthritis 5 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Asthma 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DUSP4 specifically targets JNK, and both DUSP1 and 10 have demonstrated roles in inflammation.
DUSP4 Binding (targets) of JNK associated with inflammation
1) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2970545 Disease Relevance 0.28 Pain Relevance 0.05

General Comments

This test has worked.

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