INT341614

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MOCS1) small molecule metabolic process (MOCS1) nucleus (MOCS1)
MOCS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 2 20.92 Low Low
Potency 10 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Bladder Cancer 2 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 2 5.00 Very Low Very Low Very Low
Prostate Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After a 15-minute incubation (to allow for interaction between compound and enzyme), a 1-┬ÁL substrate addition step initiated the reaction.
Positive_regulation (allow) of enzyme Binding (interaction) of
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2970562 Disease Relevance 0 Pain Relevance 0
Compound 13 additionally also reduced the apparent Km by half at a concentration of 10 nM, suggesting that the affinity of the enzyme for the substrate was increased by the inhibitor, consistent with a mode of uncompetitive or mixed-type inhibition.
Positive_regulation (increased) of enzyme Binding (affinity) of
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2970562 Disease Relevance 0 Pain Relevance 0

General Comments

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