INT341631

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (EGFR, TXK) nucleus (EGFR, TXK) cytoplasm (EGFR, TXK)
DNA binding (TXK) extracellular space (EGFR) endosome (EGFR)
EGFR (Homo sapiens)
TXK (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lung Cancer 48 96.48 Very High Very High Very High
Malignant Neoplastic Disease 8 95.96 Very High Very High Very High
Disease 17 56.68 Quite High
Disease Progression 2 47.04 Quite Low
Cancer 25 34.48 Quite Low
Non-small-cell Lung Cancer 13 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Residual Neoplasm 2 5.00 Very Low Very Low Very Low
Shock 1 5.00 Very Low Very Low Very Low
Fever 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Functional analyses of these mutant EGFRs in the cultured cells demonstrated that all EGFR mutants have enhanced tyrosine kinase activity in response to epidermal growth factor and increased sensitivity to EGFR inhibitor Erlotinib.
EGFR Positive_regulation (enhanced) of tyrosine kinase
1) Confidence 0.05 Published 2010 Journal World J Surg Oncol Section Body Doc Link PMC2970593 Disease Relevance 0.42 Pain Relevance 0

General Comments

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