INT341653

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.15
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (FGA) extracellular space (FGA) extracellular region (FGA)
plasma membrane (FGA) protein binding, bridging (FGA)
FGA (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 37 90.24 High High
Inflammation 31 63.96 Quite High
rheumatoid arthritis 8 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alpha-1-antitrypsin Deficiency 5 100.00 Very High Very High Very High
Mucocutaneous Lymph Node Syndrome 50 90.76 High High
Arthritis 34 90.24 High High
Disease 63 88.72 High High
Fever 11 66.04 Quite High
INFLAMMATION 35 63.96 Quite High
Rheumatoid Arthritis 8 5.00 Very Low Very Low Very Low
Infection 5 5.00 Very Low Very Low Very Low
Renal Disease 4 5.00 Very Low Very Low Very Low
Exanthema 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As shown in TablesĀ 6 and 7, the 17-peptide biomarkers were found to be degradation products of eight different proteins: alpha1 antitrypsin (A1AT, two peptides having overlapping sequences), collagen type I alpha 1 (COL1A1; five peptides and three of them having overlapping sequences), collagen type I alpha 2 (COL1A2; one peptide), collagen type III alpha 1 (COL3A1; one peptide), collagen type IX alpha 2 (COL9A2; one peptide), fibrinogen alpha (FGA; two peptides having overlapping sequences), fibrinogen beta (FGB; two peptides having overlapping sequences), and uromodulin (UMOD; three peptides having overlapping sequences).
fibrinogen alpha Binding (found) of associated with alpha-1-antitrypsin deficiency
1) Confidence 0.31 Published 2010 Journal Clin Proteomics Section Body Doc Link PMC2970804 Disease Relevance 1.15 Pain Relevance 0.18

General Comments

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