INT341786

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (SLC6A3) cell death (SLC6A3) aging (SLC6A3)
plasma membrane (SLC6A3) transmembrane transport (SLC6A3) cytoplasm (SLC6A3)
Anatomy Link Frequency
plasma 2
SLC6A3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cocaine 2 91.08 High High
Neurotransmitter 11 88.16 High High
Dopamine 12 58.32 Quite High
depression 8 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
sSRI 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
amygdala 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 1 71.24 Quite High
Disease 16 50.00 Quite Low
Mental Disorders 3 50.00 Quite Low
Cancer 9 5.00 Very Low Very Low Very Low
Depression 6 5.00 Very Low Very Low Very Low
Anxiety Disorder 6 5.00 Very Low Very Low Very Low
Cognitive Disorder 5 5.00 Very Low Very Low Very Low
Post-partum Depression 3 5.00 Very Low Very Low Very Low
Endometriosis (extended) 3 5.00 Very Low Very Low Very Low
Heart Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Some evidence also suggests that agents that cause DAT and SERT phosphorylation may regulate their removal from the plasma membrane and sequestration to an intracellular compartment.122–126 Protein kinases PKC and PKG and the p38 MAPK127 probably128 mediate these effects by modifying a C-terminal pentapeptide sequence that is homologous across the DAT, SERT, and NET proteins.
Positive_regulation (cause) of Phosphorylation (phosphorylation) of DAT in plasma
1) Confidence 0.16 Published 2010 Journal International Journal of Women's Health Section Body Doc Link PMC2971739 Disease Relevance 0.07 Pain Relevance 0.26

General Comments

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