INT341802

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Context Info
Confidence 0.48
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.60
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (CEP68) cytoplasm (CEP68)
CEP68 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 156 99.80 Very High Very High Very High
cINOD 15 95.32 Very High Very High Very High
Inflammation 15 93.92 High High
Analgesic 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 273 99.28 Very High Very High Very High
Occupational Lung Diseases 42 98.68 Very High Very High Very High
INFLAMMATION 21 93.92 High High
Disease 27 93.40 High High
Hypersensitivity 30 87.24 High High
Obesity 12 5.00 Very Low Very Low Very Low
Nicotine Addiction 6 5.00 Very Low Very Low Very Low
Bronchospasm 6 5.00 Very Low Very Low Very Low
Respiratory Sounds 3 5.00 Very Low Very Low Very Low
Respiratory Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, this study confers a positive association between CEP68 and aspirin-intolerant asthma, suggesting that these findings would be useful for further genetic investigations of NSAIDs metabolism as well as other inflammatory diseases.
CEP68 Binding (association) of associated with asthma, aspirin, inflammation, cinod and disease
1) Confidence 0.48 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2972220 Disease Relevance 1.13 Pain Relevance 0.33
Moreover, the follow-up study for 11 promising candidate genes increased the power to calculate the association between the CEP68 gene and aspirin intolerance in asthmatics.
CEP68 Binding (association) of associated with aspirin and occupational lung diseases
2) Confidence 0.48 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2972220 Disease Relevance 0.45 Pain Relevance 0.10
Although the inclusion of intermediate AIA in AIA case group also showed significant associations with the SNPs and haplotypes of CEP68 gene compared to ATA controls, a more correct association for genetic polymorphisms and aspirin intolerance is suggested to the comparison between AIA subjects without intermediate AIA group and ATA controls (Table 3).
CEP68 Binding (associations) of associated with asthma and aspirin
3) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2972220 Disease Relevance 1.02 Pain Relevance 0.11

General Comments

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