INT341863

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 7.39
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (RPE) cytosol (RPE) small molecule metabolic process (RPE)
carbohydrate metabolic process (RPE)
Anatomy Link Frequency
eye 4
neural retina 4
RPE (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 36 99.52 Very High Very High Very High
corticosteroid 8 94.50 High High
spinal inflammation 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 4 100.00 Very High Very High Very High
Age-related Macular Degeneration 4 100.00 Very High Very High Very High
INFLAMMATION 36 99.52 Very High Very High Very High
Cyst 20 98.94 Very High Very High Very High
Infection 28 96.52 Very High Very High Very High
Toxoplasmosis 52 95.82 Very High Very High Very High
Uveitis 208 82.24 Quite High
Disease 64 78.08 Quite High
Blindness 4 73.56 Quite High
Organ Transplantation 4 59.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
inflammatory drugs such as corticosteroids.11 In the eye, the primary target tissue for ocular toxoplasmosis is the neural retina, which displays a surrounding, intense granulomatous reaction with numerous intracellular parasite cysts.12 Free tachyzoites and cysts are also observed within retina pigment epithelium (RPE) cells.13 Ocular reactions also involve necrosis of the retina and RPE, subretinal and choroidal neovascularization, and focal inflammation.14 The inflammatory processes that are associated with retina infection by T. gondii may damage Bruch's membrane, which results in a disruption of the choroidoretinal interface.4
Negative_regulation (retina) of in neural retina Localization (neovascularization) of RPE in eye associated with necrosis, corticosteroid, inflammation, cyst, age-related macular degeneration, infection and toxoplasmosis
1) Confidence 0.03 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2972596 Disease Relevance 1.87 Pain Relevance 0.22
inflammatory drugs such as corticosteroids.11 In the eye, the primary target tissue for ocular toxoplasmosis is the neural retina, which displays a surrounding, intense granulomatous reaction with numerous intracellular parasite cysts.12 Free tachyzoites and cysts are also observed within retina pigment epithelium (RPE) cells.13 Ocular reactions also involve necrosis of the retina and RPE, subretinal and choroidal neovascularization, and focal inflammation.14 The inflammatory processes that are associated with retina infection by T. gondii may damage Bruch's membrane, which results in a disruption of the choroidoretinal interface.4
Negative_regulation (necrosis) of in neural retina Localization (neovascularization) of RPE in eye associated with necrosis, corticosteroid, inflammation, cyst, age-related macular degeneration, infection and toxoplasmosis
2) Confidence 0.03 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2972596 Disease Relevance 1.87 Pain Relevance 0.22
inflammatory drugs such as corticosteroids.11 In the eye, the primary target tissue for ocular toxoplasmosis is the neural retina, which displays a surrounding, intense granulomatous reaction with numerous intracellular parasite cysts.12 Free tachyzoites and cysts are also observed within retina pigment epithelium (RPE) cells.13 Ocular reactions also involve necrosis of the retina and RPE, subretinal and choroidal neovascularization, and focal inflammation.14 The inflammatory processes that are associated with retina infection by T. gondii may damage Bruch's membrane, which results in a disruption of the choroidoretinal interface.4
Negative_regulation (retina) of in neural retina Localization (neovascularization) of RPE in eye associated with necrosis, corticosteroid, inflammation, cyst, age-related macular degeneration, infection and toxoplasmosis
3) Confidence 0.03 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2972596 Disease Relevance 1.79 Pain Relevance 0.22
inflammatory drugs such as corticosteroids.11 In the eye, the primary target tissue for ocular toxoplasmosis is the neural retina, which displays a surrounding, intense granulomatous reaction with numerous intracellular parasite cysts.12 Free tachyzoites and cysts are also observed within retina pigment epithelium (RPE) cells.13 Ocular reactions also involve necrosis of the retina and RPE, subretinal and choroidal neovascularization, and focal inflammation.14 The inflammatory processes that are associated with retina infection by T. gondii may damage Bruch's membrane, which results in a disruption of the choroidoretinal interface.4
Negative_regulation (necrosis) of in neural retina Localization (neovascularization) of RPE in eye associated with necrosis, corticosteroid, inflammation, cyst, age-related macular degeneration, infection and toxoplasmosis
4) Confidence 0.03 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2972596 Disease Relevance 1.85 Pain Relevance 0.22

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