INT341882

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.11
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ptgs2) nuclear envelope (Ptgs2) oxidoreductase activity (Ptgs2)
endoplasmic reticulum (Ptgs2) nucleus (Ptgs2) plasma membrane (Oxtr)
Oxtr (Rattus norvegicus)
Ptgs2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
COX2 1 100.00 Very High Very High Very High
Intracerebroventricular 2 44.04 Quite Low
antagonist 38 5.00 Very Low Very Low Very Low
agonist 24 5.00 Very Low Very Low Very Low
Spinal cord 8 5.00 Very Low Very Low Very Low
Antinociceptive 8 5.00 Very Low Very Low Very Low
Neuropeptide 6 5.00 Very Low Very Low Very Low
amygdala 4 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
Dorsal horn 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 4 58.12 Quite High
Hypertension 1 27.20 Quite Low
Stress 12 18.56 Low Low
Natriuresis 1 11.84 Low Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low
Anxiety Disorder 8 5.00 Very Low Very Low Very Low
Autism 6 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low
Cognitive Disorder 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
OTR activation leads to the stimulation of phospholipase A2 production and an increase in cyclooxygenase 2 levels, both resulting in increased prostaglandin production.
Positive_regulation (activation) of OTR Positive_regulation (leads) of Positive_regulation (increase) of cyclooxygenase 2 associated with cox2
1) Confidence 0.02 Published 2010 Journal CNS Neuroscience & Therapeutics Section Body Doc Link PMC2972642 Disease Relevance 0.11 Pain Relevance 0.05

General Comments

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